GHK-Cu Cream
GHK-Cu Cream delivers a naturally occurring copper peptide directly to your skin to support firmness, smooth fine lines, and promote a healthier, more resilient complexion.
Who is this for? For those who want to support their skin's natural resilience and repair without hormonal ingredients. A strong complement to tretinoin or a standalone option for sensitive skin.
Firms and tightens aging skin
Calms redness and helps protect against daily damage
Smooths the appearance of fine lines and wrinkles
Supports your skin’s natural collagen production
* Price reflects a 6-month treatment plan. For research purposes only.
Only good stuff
GHK-Cu is a copper peptide that your body already produces, though levels drop steadily as you age. When applied topically, it signals your skin cells to ramp up collagen and elastin production, the two proteins most responsible for keeping skin firm and smooth. It also helps calm inflammation and supports your skin’s ability to repair itself from everyday wear, sun exposure, and environmental stress. The result is skin that looks and feels stronger, more even, and more resilient over time.
GHK-Cu was first isolated from human blood plasma in 1973 by biochemist Loren Pickart, who noticed that older tissue exposed to younger blood began repairing itself more like young tissue. The active compound turned out to be a small peptide with a strong attraction to copper. Since then, decades of research have confirmed its role in collagen production, wound healing, and skin remodeling. Clinical trials on topical GHK-Cu have shown measurable improvements in skin thickness, density, firmness, and fine lines, making it one of the most studied peptides in skincare science.
GHK-Cu cream is generally well tolerated. Some users may experience mild redness, slight irritation, or temporary dryness as their skin adjusts, especially during the first week or two. These effects typically resolve on their own. If irritation persists, reduce application frequency or consult your prescribing clinician.
What Sets It Apart
Your Body Already Makes It
Physician-Prescribed Strength
Backed by Decades of Research
Compounded for Quality
Frequently asked questions
GHK-Cu cream has not been approved by the U.S. Food and Drug Administration. It can only be prescribed through licensed clinicians where state law allows.
Yes. Multiple clinical trials have tested topical GHK-Cu on human skin, with results showing measurable improvements in skin density, thickness, and fine lines over 8 to 12 weeks of consistent use.
GHK-Cu stimulates your skin’s natural collagen and elastin production, calms inflammation, and supports your skin’s repair process. Over time, most users notice firmer, smoother, more even-toned skin.
GHK-Cu has been used in skincare formulations for decades with no serious side effects reported. It is a naturally occurring molecule in the human body. As with any active skincare product, use under the guidance of a licensed physician is recommended.
Individuals with a known allergy or sensitivity to copper should not use GHK-Cu cream. Pregnant or breastfeeding individuals should consult a medical professional before use.
Apply a thin layer to clean, dry skin once or twice daily on the face, neck, or chest. Apply before your moisturizer and follow with sunscreen during the day. AIRA Skin offers two strengths (0.5% and 2.0%), which you will select during your intake questionnaire for physician review.
Yes. GHK-Cu pairs well with many active ingredients and complements other AIRA Skin formulations. If you are also using a retinoid (such as tretinoin), consider applying them at different times of day. Your intake questionnaire will help determine which products work best together.
How AIRA works
Medical Intake
Prescription
Delivery
Why AIRA?
Your body already holds the blueprint — AIRA helps you unlock it. Our physician-guided peptide programs will help you perform, recover, and feel your best.
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